IntroductionEarly neurological deterioration (END) is common in acute ischemic stroke and is directly associated with poor outcome after stroke.Our aim is to develop and validate a Girls Bag nomogram to predict the risk of END after mechanical thrombectomy (MT) in acute ischemic stroke patients with anterior circulation large-vessel occlusion.Metho
Antibiotic resistance is a major public health concern.The shrinking selection of effective antibiotics and lack of new development is making the situation worse.Gram-negative bacteria more specifically pose serious threat because of their double layered cell envelope and effective efflux systems, which is a challenge for drugs to penetrate.One pro
BACKGROUND: The central paradigm of ecological immunology postulates that selection acts on immunity as to minimize its GINGER cost/benefit ratio.Costs of immunity may arise because the energetic requirements of the immune response divert resources that are no longer available for other vital functions.In addition to these resource-based costs, mis